Program

Monday Oct 7th
08:30-09:00 Registration

Session 1

09:00-09:30 Welcome address
09:30-11:00
Inaugural Keynote Lecture
Manuel Serrano
Decoding the Role of Mitochondria in Cellular Senescence
Selected talk #1
Juan Pedro Martinez-Barbera
Uncovering the role of cellular senescence in pediatric and adult cancer by using novel mouse models that report and ablate senescent cells
Selected talk #2
Marta Magariños
Altered developmental senescence as the basis of CHARGE syndrome inner ear defects
Selected talk #3
Marta Lalinde Gutiérrez
Unravelling the dual role of senescent cells in breast cancer progression
11:00-11:30 COFFEE BREAK

Session 2

11:30-13:00
Invited Speaker #1
Elsa Logarinho
UnFOXingAge – The geroprotective role of transcription factor FOXM1
Invited Speaker #2
Carlos Anerillas
Exploring the connections and causal links between senescence and fibrosis through the matrisome
Selected talk #4
Daniel Humphreys
Understanding acute host senescence responses to the typhoid toxin of Salmonella Typhi
Selected talk #5
Florencia Herbstein
Amplification of pituitary tumor senescence by IL-6: A mechanism to control tumor expansion
Selected talk #6
Alba García Fernández
Galacto-activatable senoprobes for the real-time detection of cellular senescence
13:00-14:30 LUNCH

Session 3

14:30-16:00
Invited Speaker #3
Björn Schumacher
A DREAM Master Regulator of Genome Stability and Aging by the Clock yet without a Program
Invited Speaker #4
Sofía Ferreira
Cellular senescence: the ‘ACHILLES’ HEEL’’ of liver transplantation
Selected talk #7
Alejandro Failde-Fiestras
The Last Kiss: Apoptotic Secreted Factors drive Apoptosis-Induced Senescence (AIS)
Selected talk #8
Akang Leonard Bassey
Senescent cell ablation and modulation of their secretome prevents tumor formation in mouse models of adamantinomatous craniopharyngioma.
Poster Teasers
16:00-16:30 COFFEE BREAK

Session 4

16:30-18:00
Invited Speaker #5
Daniel Muñoz-Espín
Urinary detection of senescence during lung cancer chemotherapy and pulmonary fibrosis via an MMP-7 activatable nanosensor
Invited Speaker #6
Marta Montes
RNA-based mechanisms regulating cellular senescence
Selected talk #9
Sabela Da Silva Álvarez
Identifying biomarkers of senescence after chemotherapy to guide cancer treatment
Selected talk #10
Pablo Palau
Cellular senescence in the regeneration of Syllis malaquini (Syllidae, Annelida)
Poster Teasers
18:00-20:00 POSTER SESSION & DINNER
Tuesday Oct 8th

Session 5

09:30-11:00
Invited Speaker #7
Masashi Narita
Cellular functionality and plasticity in the senescence spectrum
Invited Speaker #8
Maria Abad
Therapy-induced Senescence (TIS) in Pancreatic Cancer: Implications for Immune Response and Therapeutic Strategies.
Selected talk #11
Victor Núñez-Quintela
Senomorphic effect of partial reprogramming
Selected talk #12
Domenico Aprile
Advances in senolytic therapies: Piceatannol in combating cellular senescence
Selected talk #13
Gema López Pernas
A one-two-punch approach in cancer therapy. Trying to discover the second punch.
11:00-11:30 COFFEE BREAK

Session 6

11:30-13:00
Invited Speaker #9
Han Li
New tricks of an old player: senescence induced-cellular plasticity in health and disease
Invited Speaker #10
Jose A Lopez Dominguez
Exploring and leveraging metabolic features of senescent cells.
Selected talk #14
Miguel Ángel Prados
Identifying Compounds Targeting Senescent Cells Using High-Throughput Screening
Selected talk #15
Maria P. Ikonomopoulou
A new class of senolytics derived from animal venoms
Selected talk #16
Paula M. Soriano-Teruel
A dual-targeted nanodevice for the selective elimination of senescent cells in idiopathic pulmonary fibrosis
13:00-14:30 LUNCH

Session 7

14:30-16:00
Selected talk #17
Christian Fernandez
Unveiling Senescence’s Shadows: Targeting TMPRSS11a for Selective Senescent Cell Elimination
Selected talk #18
Naroa Goikoetxea-Usandizaga
Role of Glutaminase isoform1 (GLS1) in Liver Senescence via Ammonium and Iron Modulation
Selected talk #19
Rocío M. Tolosa
Cellular senescence as the basis for HCMV-related pathogenesis
Closing Keynote Lecture
Myriam Gorospe
Insights from Senescence into Age-Associated Neurodegeneration
16:00 CLOSING REMARKS
16:30 GENERAL ASSEMBLY (SENESCEL members only)
18:00 FREE CITY GUIDED TOUR (1:30-2:00 h)
18:30
AFUNDACIÓN-SENESCEL-ColladoLab
“Conversaciones sobre Envejecimiento: Myriam Gorospe & Manuel Collado”
Free and opened to general audience (session in Spanish)
21:00 GALA DINNER